Pursuant to the Foreign Assistance Act of 1961, as amended, the United States Government, as represented by the U.S. Agency for International Development (USAID), the Bureau for Development, Democracy, and Innovation (DDI), Inclusive Development Hub (ID) is announcing the Alliance to Advance Protection and Care for Children in Adversity (APCCA) Annual Program Statement (APS). Through the APCCA Alliance APS, USAID aims to address key objectives outlined in the U.S. Government (USG) Advancing Protection and Care for Children in Adversity Strategy. The purpose of this APS is to disseminate information to prospective Applicants so they may develop and submit Concepts in response to future Addenda under this APS and ultimately to be considered for USAID funding. USAID DDI/ID anticipates awarding multiple grants and/or cooperative agreements as a result of this APS. However, issuance of this APS does not constitute an award commitment on the part of the U.S. Government, nor does it commit the USG to pay for any costs incurred in the preparation or submission of comments/suggestions, a concept, or an application. Concepts and Applications are submitted at the risk of the applicant. All preparation and submission costs are at the applicants expense. The actual number of assistance awards, if any, under this APS is subject to the availability of funds and the interests and requirements of Operating Units (OUs) as well as the viability of eventual Full Applications received. There is no predefined minimum or maximum number of awards USAID OUs will support through this APS. The APCCA APS is unfunded and serves as a general umbrella APS, to which any USAID OU can post specific Addenda that are focused on challenges or priorities highlighted in the APS. An Addendum highlights a specific program or activity, where technical assistance or partnership opportunities are communicated by a USAID OU. Addenda will be the exclusive source of funding through this APS. NOTE: This APS is not a Request for Applications or a Request for Proposals, and does not serve as a general request for APCCA concepts. USAID will only consider Concepts that are submitted in response to Addenda to this APS. USAID will not accept or consider any Concepts submitted in response to the general APCCA Alliance APS. Addenda will be posted on www.grants.gov. Based on the submitted Concept(s) to specific Addenda opportunities, USAID will determine whether to engage in more in-depth and specific co-creation discussions aimed at further developing the proposed approach and will determine whether to request a Full Application. To be competitive under a particular Addendum to this umbrella APS, Concepts and Full Applications must be fully responsive to all directions under this APS document except when specifically noted otherwise in the Addendum. Please refer to the full APS document attached for full information and details about this opportunity.