The purpose of this NOFO is to build on the previous RPE NOFO, CDC-RFA-CE19-1902, by continuing to enhance the capacity of state and territorial health departments (hereafter referred to as SHDs) to facilitate and monitor the implementation of sexual violence (SV) prevention programs, practices, and policies. This five-year funding opportunity requires that recipients build infrastructure for SV prevention; develop/enhance a state/territory action plan; implement community- and societal-level SV prevention strategies that promote health equity; and utilize data to inform action. Completing these activities should lead to increased capacity to promote health equity, capacity to implement/evaluate SV prevention at the community- and societal-levels, increased partner and community awareness of effective prevention strategies, and increased partner coordination to prevent SV. Completion of these activities should also result in increased community-level implementation of SV prevention strategies, implementation of prevention strategies that reach high-burden communities and address social determinants of health (SDOH), use of data to understand inequities, and monitoring and evaluation activities related to SV prevention. The activities outlined in this NOFO will build the foundation for recipients to decrease rates of SV perpetration and victimization at the state/territory level and reduce disparities in SV by addressing associated inequities in social and structural determinants of health.