NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)

The National Institute on Deafness and Other Communication Disorders (NIDCD), a division of the National Institutes of Health (NIH), plans to reissue a Notice of Funding Opportunity (NOFO) for Clinical Research Center Grants, continuing from a prior opportunity (PAR-22-025). This grant opportunity is designed to support integrated, multidisciplinary clinical research in the areas of hearing, balance, smell, taste, voice, speech, or language. The research must involve individuals or data from individuals with sensory or communication disorders. The Clinical Research Center Grant (P50) aims to provide a structured yet flexible framework to address complex clinical problems through synergistic research. Eligible proposals must include a collaborative, multidisciplinary team undertaking 3 to 4 research projects unified under a central theme. These projects should be integrated to produce outcomes that exceed the impact of individual efforts. The structure includes an administrative core and optionally one to two scientific cores to ensure operational efficiency and scientific rigor. This funding opportunity supports clinical research defined as studies involving individuals with sensory and communication disorders or their derived data/tissues. Projects may include low-risk clinical trials, although such trials are not mandatory. The objective is to stimulate novel, impactful research that can significantly advance understanding and treatment in the relevant clinical domains. Eligibility is broad, encompassing a range of organizations including state and county governments, tribal governments and organizations, higher education institutions, public housing authorities, school districts, small and large businesses, and nonprofit organizations with 501(c)(3) IRS status. This inclusiveness encourages diverse collaboration and participation in addressing critical research questions. As of the current notice, applications are not being accepted. This forecast serves to inform potential applicants and give them sufficient time to form collaborations and prepare responsive applications. The formal Notice of Funding Opportunity will open on August 6, 2025, with a due date of October 7, 2025. Awards are expected to be announced by July 7, 2026, with the same date set for project start. For more information, interested parties can contact Dr. Holly Storkel at the NIDCD via email at holly.storkel@nih.gov or by phone at 301-496-5061.